Real Madrid striker, Kylian Mbappe, missed his second penalty in one week as they lost 2-1 to Athletic Club on Tuesday.
It was Los Blancos’ fourth loss in their last seven games in all competitions.
Athletic took the lead thanks to Alex Berenguer’s effort in the 53rd minute.
Mbappé had the chance to level from the spot, but he stroked another weak shot that was saved by Julen Agirrezabala.
Madrid equalized in the 78th minute when Jude Bellingham fired home a rebound.
However, an error by Federico Valverde saw the ball break for Gorka Guruzeta to score the winner one minute later.
Madrid missed the chance to close the gap on leaders Barcelona, who top the standings on 37 points, four ahead of second-placed Real who have a game in hand. Athletic are fourth on 29 points.